Category Archives: Turmeric

Study Shows Curcumin Works As Well As Herceptin In Some Cases

http://MarnieClark.com/Study-Shows-Curcumin-Works-As-Well-As-Herceptin-In-Some-CasesStudy Shows Curcumin Works As Well As Herceptin In Some Cases

While doing some research for one of my newsletters about curcumin, the pigment derived from the root spice turmeric, and its good effects for breast cancer, I ran across a study on curcumin that had some great information for those with HER2 positive breast cancer.

About 15-25 percent of breast cancer patients are HER2 positive, meaning that their tumors have an overexpression of this oncoprotein which researchers have observed is associated with a poor prognosis, increased disease recurrence and metastases. One of the drugs that has been created to address this problem is trastuzumab, also called Herceptin.

There is little doubt that Herceptin is saving lives, but there’s a problem for some people.

Quite a few women have contacted me from various parts of the world where Herceptin is either not available or too expensive – Africa being the main location where this is happening. These women have been diagnosed with HER2 positive breast cancer and are quite concerned that Herceptin is not available for them.  Another couple of problems exist as well. The tumor cells of some women have a resistance to Herceptin. And for some, Herceptin is too hard on their heart and/or lungs. So it is for these women that I am sharing this information.

The study I read was released in 2012 and its title is “The Potential Utility of Curcumin in the Treatment of HER-2-Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin” [1].

As denoted by the title, the study was both an in vitro (test tube) study and in vivo (in body – with animals) study done with various lines of breast cancer cells and on mice. I believe the results are very interesting and are certainly worth considering, especially in view of the fact that not everyone has access to the drug Herceptin, some are resistant and some are just not able to tolerate it. These people need Herceptin alternatives.

The Research

Researchers wanted to gain some insight about what worked best for tumors that overexpress the HER2 oncoprotein. So they divided up various lines of breast cancer cells (listed below) in test tubes and also test animals into 8 different groups:

1. Those who received DMSO only
2. Those who received Herceptin only
3. Those who received curcumin only
4. Those who received a combination of Herceptin and curcumin
5. Those who received Taxol only
6. Those who received a combination of Taxol and Herceptin
7. Those who received a combination of Taxol and curcumin
8. Those who received a combination of Taxol, curcumin and Herceptin

The results revealed that curcumin reduced the cell viability of several different breast cancer cell lines, including MCF-7 (ER-positive, HER-2-negative), MDA-MB-231 (ER-negative, PR-negative, HER-2-negative – also known as triple negative), BT-474 (ER-positive, HER-2-positive), and SK-BR-3-hr (ER-negative, HER-2-positive but Herceptin-resistant) cells.

Herceptin Combined with Curcumin

Researchers found that when a low dose of Herceptin was used with curcumin, there was a synergistic effect, but when a high dose of Herceptin was used, there was an antagonistic effect, meaning that the combination didn’t work as well. So for someone having high doses of Herceptin, taking curcumin would most likely not provide an advantage.

In BT-474 cells (ER-positive, HER-2 positive), curcumin effectively decreased tumor size.

Also, researchers noted that curcumin had the ability to inhibit Herceptin-resistant breast cancer cells (SK-BR-3). This is of great importance to those who are HER2 positive but who are resistant to Herceptin. Researchers stated “The ability of curcumin to downregulate EGFR and HER-2 oncoproteins and inhibit the phosphorylation of Akt and MAPK and NF-kB activation suggests that curcumin has potential in the treatment of HER-2-overexpressed and/or herceptin-resistant breast cancer.”

In the animal study, curcumin treatment effectively reduced the tumor size by 76.7%, compared with the control; however, it was not as effective as Herceptin, which achieved an 86.7% tumor reduction.

Did you get that? Curcumin alone reduced tumor size by 76.7%. Yes, Herceptin did a better job, it reduced tumor size by 86.7% but Herceptin is also pretty hard on the body and curcumin is not.

Researchers also revealed that the combination of Herceptin and curcumin showed a greater antitumor effect than curcumin alone (87.5% versus 76.7% in tumor regression).

Interestingly, researchers anticipated the study to reveal that there would be a synergistic effect when combining Herceptin with curcumin, but in the animal study, combining Herceptin and curcumin was no better than Herceptin alone.

Taxol Combined With Curcumin

In the animal study, the combination of curcumin with Taxol had an antitumor effect comparable with combining Taxol and Herceptin, which is one of the current preferred chemotherapy regimens for those with HER2 positive breast cancer. The combination of Taxol, Herceptin and curcumin was associated with the smallest tumors, but was not “statistically different” from that of the Taxol and Herceptin regimen.

I take that last paragraph to mean that combining Taxol with curcumin is just as good as combining Taxol and Herceptin. That’s huge! And combining Taxol, Herceptin and curcumin provided the best results in the animal study.

In conclusion, I believe this study is significant. In people who do not tolerate Herceptin well or are unable to get this drug due to finances or geographical location, or for those whose tumor cells are Herceptin resistant, according to this study, the combination of Taxol and curcumin is just as good as combining Taxol and Herceptin.

For dosage advice of curcumin, see my article: Harvest The Power Of Curcumin To Kill Breast Cancer Cells.

References:
1. The Potential Utility of Curcumin in the Treatment of HER-2-Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin – http://www.hindawi.com/journals/ecam/2012/486568/

GET MY BEST TIPS on getting through breast cancer and preventing recurrences by signing up for my free e-newsletters and e-books on the right.  You can also “like” me on Facebook (Marnie Clark, Breast Health Coach) to get my inspirational snippets, news and updates.  I promise to do my utmost to keep you informed and empowered on your healing journey… and beyond.  

Does Curcumin Have An Estrogenic Effect?

http://MarnieClark.com/ Does-Curcumin-Have-An-Estrogenic-EffectDoes Curcumin Have An Estrogenic Effect?

This week I received a very helpful and enlightening newsletter from Dr Jacob Schor, Naturopath, titled Does Curcumin Have An Estrogenic Effect? and I wanted to share it with you.

Dr Schor is also on the Board of Directors for the Oncology Association of Naturopathic Physicians and is based in Denver, Colorado.  He is often quoted on this website because of his excellent research skills, quality information and helpful insights for the breast cancer community.

Dr Schor has very kindly allowed me to copy the contents of his newsletter for you to read:

Does Curcumin Have An Estrogenic Effect?
By Jacob Schor, ND, FABNO
www.DenverNaturopathic.com
September 27, 2015

Over the last month or so, several patients have contacted me in great concern because they had read online that curcumin (the turmeric extract) has estrogenic effect and is thus contraindicated in any estrogen sensitive cancer, in particular, breast cancer.  Thus I am obligated to consider and answer this question in great detail.  For those of you who simply want the bottom line: many things you read online are not true. This is one of them.  Curcumin is still strongly indicated for use in all types of breast cancer.

This concern appears to have been started by an inaccurate statement on WebMD: “Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, turmeric might make hormone-sensitive conditions worse. However, some research shows that turmeric reduces the effects of estrogen in some hormone-sensitive cancer cells. Therefore, turmeric might have beneficial effects on hormone-sensitive conditions.   Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones 1.

This statement in various versions has been copied and pasted onto a growing number of other websites.

The WebMD article did not cite a source for this idea.  In a situation in which one makes a statement that runs contrary to general consensus, it is typically expected to be justified with a reference.

Our assumption is that WebMD’s statement is based on a 2010 paper by Bachmeier et al as it is the only study that we’ve found to suggest the idea that curcumin is at all estrogenic:
http://www.ncbi.nlm.nih.gov/pubmed/20798532

Bachmeier et al examined the impact of curcumin, along with quercetin and the enterolactones (derived from flax) on the expression of the  genes in breast cancer cells that are normally strongly stimulated by estrogen.  “Gene regulation induced by these compounds was low for genes strongly induced by E2 and similar to the latter for genes only weakly regulated by the classic estrogen. Of interest with regard to the treatment of menopausal symptoms, the survival factor…” 2

Bachmeier found that curcumin has a very weak estrogen-like effect on these genes. The authors of the paper were not worried about breast cancer stimulation, rather they were wondering if these compounds might decrease hot flashes.

We should note that the same authors have published other papers on curcumin and breast cancer, all focused on its potential benefit in treating this type of cancer.  They do not seem the least bit concerned about an estrogenic effect, nor do they appear to be the least concerned about their findings.  Here are a few other titles from these same researchers:

2008 “Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NfkappaB.” 3

2007 “The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice.” 4

2010 “Curcumin, either as an isolated chemoprevention substance or in combination with chemotherapeutic agents as supportive measure reducing pharmaceutical resistance of tumor cells to certain chemotherapeutics” 5

My colleague Lise Alschuler, author of “The Definitive Guide to Cancer, 3rd Edition: An Integrative Approach to Prevention, Treatment, and Healing”, when asked about this commented that the concern was based only on “… in vitro indirect data – so [it is] bogus. Every plant would have some phytoestrogenic properties in a petri dish and this one was weak.”

I also contacted Bharat Aggarwal who directs the MD Anderson’s research laboratory, which has done much of the published research on curcumin, to ask if this idea was possibly true.  His response: “…there is no evidence for this.”

To paraphrase another colleague, Paul Reilly ND, FABNO, ‘Almost all flavonoid molecules have some mildly estrogenic effect.  In the case of curcumin this effect is quite weak and is far outweighed by its other anti-cancer actions. These estrogenic effects themselves, though mild can be considered anti-estrogenic in that they compete for the ER binding sites on cells, like a very weak form of tamoxifen.’

So where does that leave us?  There seems to be no evidence to support the idea that patients should be concerned about estrogenic effects from curcumin.

This should serve as a lesson to all of us, that, as we move forward through this journey of living with cancer, science and medicine,  we take careful steps; we need to be cautious regarding what we read and believe to be fact.  The idea that curcumin should be avoided appears to have no credible evidence to support it.  Yet as a result, many patients may be hesitant to use something that could have potential benefit in their lives.

References:

1.  http://www.webmd.com/vitamins-supplements/ingredientmono-662-Curcumin%20%28TURMERIC%29.aspx?activeIngredientId=662&activeIngredientName=Curcumin%20%28TURMERIC%29

2. Bachmeier BE1, Mirisola V, Romeo F, Generoso L, Esposito A, Dell’eva R, Blengio F, Killian PH, Albini A, Pfeffer U. Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin. Cell Physiol Biochem. 2010;26(3):471-82.

3. Bachmeier BE1, Mohrenz IV, Mirisola V, Schleicher E, Romeo F, Höhneke C, Jochum M, Nerlich AG, Pfeffer U. Curcumin downregulates the inflammatory cytokines CXCL1 and -2 inbreast cancer cells via NFkappaB. Carcinogenesis. 2008 Apr;29(4):779-89. Epub 2007 Nov 13.

4. Bachmeier B1, Nerlich AG, Iancu CM, Cilli M, Schleicher E, Vené R, Dell’Eva R, Jochum M, Albini A, Pfeffer U. The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice. Cell Physiol Biochem. 2007;19(1-4):137-52.

5. Bachmeier BE1, Killian P, Pfeffer U, Nerlich AG. Novel aspects for the application of Curcumin in chemoprevention of various cancers Front Biosci (Schol Ed). 2010 Jan 1;2:697-717.

Thank you Dr Schor for setting the matter straight for us in the breast cancer community and for going to all of the trouble to make phone calls and delve into the research.  We thoroughly appreciate your time and attention.

For more information on how curcumin is beneficial for breast cancer, dosages and specific supplements see my article Harvest The Power Of Curcumin To Kill Breast Cancer Cells.

GET MY BEST TIPS on getting through breast cancer and preventing recurrences by signing up for my free e-newsletters and e-books on the right.  You can also “like” me on Facebook (MarnieClark.com) to get my inspirational snippets, news and updates.  I promise to do my utmost to keep you informed and empowered on your healing journey… and beyond. 

Going Through Radiotherapy For Breast Cancer? Better Take Curcumin!

Image Source: freedigitalphotos.net / artur84
Image Source: freedigitalphotos.net / artur84

Going Through Radiotherapy For Breast Cancer?  Better Take Curcumin!

If you are currently going through radiotherapy for breast cancer, you would be well advised to include curcumin in your daily supplement regime.  I’ll share why in a moment.

First, however, a little rant.  I am frequently told by women going through breast cancer that when they asked their oncologist or their radiologist whether there were certain supplements which would help them get through the treatments, without much variation they are told “Just eat what you want to, evidence doesn’t support that a certain diet or supplements will help you.”

THIS IS JUST PLAIN WRONG!

Anyone who advises that nutrition is unimportant for people going through cancer is both ill-informed and dangerous.  Ill-informed because the research is out there!  Evidence that nutrition makes a huge difference is comprehensive.   And I say they are dangerous because such advice causes vulnerable people to ignore or disregard a source of significant help which would improve both their quality of life and their survival.   Good nutrition can indeed reduce the risk of developing cancer, it can slow the rate of progression, and it can very effectively stop recurrences.  Okay, rant over.  Back to curcumin and how it can help with radiotherapy.

Should you not be familiar with curcumin, it is a yellow pigment derived from turmeric, a common root used for spice and cooking.

In a 2007 study, Radioprotection and Radiosensitization By Curcumin, researchers found that  curcumin “…has been reported to protect various study systems against the deleterious effects induced by ionizing radiation and to enhance the effect of radiation. Therefore, curcumin can be very useful during radiotherapy of cancer.  Administration of curcumin in patients will be able to kill the tumor cells effectively by enhancing the effect of radiation and, at the same time, protect normal cells against the harmful effects of radiation.”

In plainer language, this means that curcumin was found to be protective against the harmful effects that occur as a result of radiotherapy, and that curcumin actually enhanced the effect of radiotherapy.

The available information on curcumin suggests that its protective effects may be due to its ability to reduce oxidative stress and inhibit transcription of the genes related to oxidative stress and inflammatory responses.  In addition, curcumin’s ability to enhance radiotherapy could be due to the upregulation of genes responsible for cell death.

A newer Iranian study published in 2013 and done with prostate cancer patients, A Pilot Clinical Trial of Radioprotective Effects of Curcumin Supplementation in Patients with Prostate Cancer found that “Curcumin can confer radioprotective effect in patients with prostate cancer who undergo radiation therapy through reducing the severity of radiotherapy related urinary symptoms.”

I think the best article, and the most relevant one to date is The Effect Of Curcumin On Breast Cancer Cells published in the Journal of Breast Cancer in June 2013.  Although this one didn’t study curcumin’s effects for those going through radiotherapy for breast cancer, take the time to read the study because it will make a believer out of you that curcumin has a powerful chemotherapeutic role to play in the treatment of breast cancer.

For more information about curcumin, particularly its benefits for cancer patients, and for specific dosages, see my article Harvest the Power of Curcumin To Kill Breast Cancer Cells.

GET MY BEST TIPS on getting through breast cancer and preventing recurrences by signing up for my free e-newsletters and e-books on the right.  You can also “like” me on Facebook (MarnieClark.com) to get my inspirational snippets, news and updates.  I promise to do my utmost to keep you informed and empowered on your healing journey… and beyond.  

Harvest the Power of Curcumin To Kill Breast Cancer Cells

Image source: freedigitalphotos.net / Sommai

Image source: freedigitalphotos.net / Sommai

Harvest The Power Of Curcumin To Kill Breast Cancer Cells

The world now has plenty of information about how the root turmeric packs a punch against cancer cells through the active pigment within it, known as curcumin.  I just read that in the last 10 years, over 4,600 research studies have been done on curcumin and some of those studies are revealing some very interesting information on exactly how curcumin works against cancer.

One of the most interesting things we have learned about curcumin is that it has chemopreventive action, which means that it is able to interfere with a disease process.  Chemopreventive agents are used to inhibit, delay or reverse carcinogenesis, the process by which normal cells turn into cancer cells.

Curcumin Works In Many Different Ways

Chemopreventive agents are broken down into 3 sub-groups: antioxidants, anti-proliferants and carcinogen blockers.  Curcumin has the distinction of being in all three sub-groups – meaning that it works against cancer in these three different ways.  It also works in several different pathways of the body that regulate programmed cell death, which is also important.

The human body consists of 10-13 trillion cells – that’s one million million!  These cells turn over, on average, approximately every 100 days.  Some cells, for instance skin cells, take much less time to regenerate, and some take more, like bone cells.   About 100 billion cells have to die every day to make room for the new crop, through a process called apoptosis (pronounced a-pop-TOE-sis).

The problem with cancer cells is that they don’t die off through that natural process of apoptosis when they are supposed to. They just keep growing and multiplying, out of control.  They do this by somehow turning off the genes necessary to cause apoptosis.

Curcumin To The Rescue!

We now have some great research which shows all of the ways that curcumin spells death to cancer cells.   It is able to do this in so many ways, for a complete understanding you’ll need to read the research paper listed at #6 below.  Here are a dozen of the most important ways curcumin protects our cells:

  1. Curcumin upregulates DR5 (death receptor 5), a human gene which encodes certain proteins;
  2. Curcumin upregulates the FAS receptor gene, which plays a central role in the regulation of programmed cell death;
  3. Curcumin activates certain enzymes which destroy cancer cells from within;
  4. Curcumin increases tumor cell sensitivity to chemotherapy and radiation therapy;
  5. Curcumin inhibits cancer cell division, growth and metastasis;
  6. Curcumin increases cancer cell death;
  7. Curcumin inhibits tumor cell survival;
  8. Curcumin inhibits growth of blood vessels to tumors, a process known as angiogenesis;
  9. Curcumin is strongly anti-inflammatory;
  10. Curcumin acts as an antioxidant;
  11. Curcumin inhibits carcinogenic agents;
  12. Curcumin protects normal tissues (liver, kidney, mucous membranes, heart, etc) from the harmful effects of radiation and chemotherapy.

Why curcumin kills tumor cells and leaves healthy cells alone is not well understood but this is indeed the case.  Tumor cells also don’t appear to develop a resistance to curcumin the way they tend to do with chemotherapy drugs.  This makes curcumin a very useful therapeutic supplement both for those wishing to keep cancer away, and for those actively battling cancer.

Curcumin and HER2 Positive Breast Cancer

One of the most interesting research studies I found indicated that curcumin has potent effects against the HER2 oncoprotein.  For those with this sort of breast cancer, this is very good news.  It was found that the combination of the chemotherapy drug taxol and curcumin had an antitumor effect comparable with taxol and herceptin, the drug most commonly prescribed for those with HER2 positive breast cancer. 5

What Is An Effective Dose?

This is the most asked question for integrative doctors, naturopaths and health coaches.  And of course, we don’t all agree, nor are there conclusive studies which indicate what the therapeutic dose is.  But please read on!

According to Dr Brian Lawenda (a very talented integrative oncologist, Dr Lawenda has an excellent website, see the link below at #1), one study indicated that up to 8 grams (8,000 mg) per day for three months was an effective dose to reduce the progression of precancerous lesions of the mouth, skin, stomach and cervix.

Another study indicated that curcumin is poorly absorbed by the bowel but able to concentrate in intestinal tumors quite well in patients with advanced colorectal cancer.  These patients took 3.6 grams/day of curcumin orally for 7 days.

From all of the reading and research I have done in the past years, this is what I have learned about therapeutic dosing of curcumin and this is what I recommend for my clients:

Curcumin Dosage Advice:

1.  Absorption of curcumin can be increased when taken with piperine, which is an extract from black pepper.  Combining these two has been shown to increase curcumin absorption by up to 2,000%.  Certain health supplement companies have created formulations that have greater absorption characteristics, and I will link to a couple of  very good curcumin supplements below.
2.  To maintain high blood levels of curcumin and receive the best effects, it is best to take it in divided doses, three times per day – and with meals – as it is better absorbed with food that contains healthy fats such as olive oil, coconut oil, oily fish, avocados, full fat (organic) milk, walnuts, seeds, etc.
3.  Dr Brian Lawenda recommends that for the purposes of preventing cancer, 500 mg per day is suggested and, indeed, the doctor known as the Curcumin Guru (and one of the co-authors of research article 6 below) takes this dosage.  During and after cancer treatment, Dr Lawenda advises taking 800-3,000 mg per day, in divided doses, with meals.
4.  The latest scuttlebutt amongst natural health professionals indicates that the whole turmeric root (it looks a lot like ginger) is even more potent.  In preliminary research (yet to be published), the turmeric dose required to suppress cancer cell growth was one thousand percent smaller than the curcumin dose, so I would highly recommend using the natural root of turmeric in your cooking whenever possible.

Here are two extremely good curcumin supplements, I highly recommend them.

References:

1.  Dr Brian Lawenda’s article on curcumin:  http://www.integrativeoncology-essentials.com/2013/03/is-there-any-other-anti-cancer-botanical-compound-as-exciting-as-curcumin/

2.  http://tv.greenmedinfo.com/turmeric-kills-cancer-cells/

3.  2014 Research: New Perspectives of Curcumin in Cancer Prevention: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693758/

4.  2013 Research: Curcumin for Radiation Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Thirty Breast Cancer Patients — http://www.rrjournal.org/doi/abs/10.1667/RR3255.1

The Effect of Curcumin on Breast Cancer Cells — http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706856/

5.  2012 Reseach: The Potential Utility of Curcumin in the Treatment of HER-2-Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin — http://www.hindawi.com/journals/ecam/2012/486568/

6.  2009 Research: Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively? — http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758121/

GET MY BEST TIPS on getting through breast cancer and preventing recurrences by signing up for my free e-newsletters and e-books on the right.  You can also “like” me on Facebook (MarnieClark.com).  I promise to do my utmost to keep you informed and empowered on your healing journey… and beyond. 

 

Curcumin Very Helpful For Those With Resistance to Chemotherapy, Tamoxifen

Photo courtesy of rgbstock.com and Tacluda
Photo courtesy of rgbstock.com and Tacluda

Curcumin Very Helpful For Those With Resistance To Chemotherapy, Tamoxifen

According to breastcancerresearch.com, approximately 70% of breast cancers are estrogen receptor positive (ER+) at diagnosis.  These patients are often recommended to have endocrine therapies that target estrogen receptors, such as the drug Tamoxifen.

Tamoxifen works by binding to tissues that use estrogen. This binding blocks the action of estrogen in the breast but mimics the action of estrogen in the bones and uterus.  Tamoxifen is used to treat ER+ breast cancer in men and women and to prevent breast cancer in those at high risk.

Some People Are Resistant

Some people, however, are resistant to anti-estrogenic drugs like Tamoxifen, and also to certain chemotherapy drugs.  See my article about chemoresistance, Chemo-Resistant Breast Cancers In The News.  This has proven to be a huge problem for some patients.

According to breastcancerresearch.com development of resistance is a process that “appears to result from upregulation of growth factor and protein kinase signaling pathways that provide an alternate mechanism in support of tumor cell proliferation and survival.”  So researchers are keen to identify or target the factors that come into play with endocrine resistance.

Some progressive oncologists are utilizing the chemosensitivity test for their patients who are resistant to certain chemo drugs.  See my article If You Are Contemplating Chemotherapy, You Should Know About the Chemosensitivity Test.

Curcumin To The Rescue

The good news is that a new Chinese study, published in January 2013 in Molecules, indicates that curcumin, the active ingredient in turmeric, has been shown to be effective in helping to restore Tamoxifen sensitivity and also sensitizes cancer cells to chemotherapy, thus making the chemotherapy more effective.  The researchers “discovered that curcumin treatment displayed anti-proliferative and pro-apoptotic activities” and that the “findings suggested that curcumin alone and combinations of curcumin with endocrine therapy may be of therapeutic benefit for endocrine-resistant breast cancer.  Click this link to read the Chinese study.

You can get curcumin in capsules in health food stores, you can also use turmeric in your cooking.   Allrecipes.com has a big list of recipes that utilize turmeric.  It’s a gorgeous spice and adds depth and flavor to your curries, as well as other dishes.  I recommend turmeric in my page Diet and Cancer (scroll all the way to the bottom).

References:

http://breast-cancer-research.com/content/13/3/R70

http://www.ncbi.nlm.nih.gov/pubmed/23299550

If you would like my help with getting through breast cancer in an inspiring and ultra-healthy way, please sign up for my free e-newsletters on the right, or “like” me on Facebook (MarnieClark.com).  It is my honor and my goal to help you through this.